Ying ZHANG

Personal Information

Title: Associate Professor

Department: Department of Biochemistry and Molecular Biology

Email: zzhangying@hust.edu.cn

Clinical Focus:

Research Focus/Interests: the molecular events of atherosclerosis; vascular remodeling; endoplasmic reticulum stress in atherosclerosis

Biography

2009-present   Associate Professor
Department of Biochemistry and Molecular Biology, Huazhong University of Science and Technology
2007-2009     Post-doc,  renal medicine
McMaster University, Canada
2006-2007    Lecture
Department of Biochemistry and Molecular Biology, Huazhong University of Science and Technology

Courses Taught:
Biochemistry (undergraduate)
The experimental technique of  biochemistry (undergraduate)
Problem based learning (undergraduate)
Molecular biology: Theory and Applications (graduate)

Education

PhD in internal medicine, 2006, Wuhan University 
BS in clinical medicine, 2001, Wuhan University

Boards, Advisory Committees, Professional Organizations

Publications

1.	Zhang Y, Peng F, Gao B, Ingram AJ, Krepinsky JC. Mechanical strain-induced ROS activation requires NADPH oxidase mediated ROS generation in caveolae. Antioxid Redox Signal, 13(7):959-973, 2010. 
2.	Du H, Li W, Wang Y, Chen S, Zhang Y*. Celecoxib induces cell apoptosis coupled with up-regulation of the expression of VEGF by a mechanism involving ER stress in human colorectal cancer cells. Oncol Rep, 26(2): 495-502, 2011. 
3.	Zhang Y, Peng F, Gao B, Ingram AJ, Krepinsky JC. High glucose-induced RhoA activation requires caveolae and PKCβ1-mediated ROS generation. Am J Physiol Renal Physiol, 302(1): F159-172, 2012. 
4.	Du HS*, Wang Y*, Zhang ZF, Yang J, Zhang J, Zhang Y#. Fibronectin modulates formation of macrophage foam cells by activating SREBP2 involved in endoplasmic reticulum stress. Cellular Physiology and Biochemistry. Cell Physiol Biochem. 2015;36(5):1821-1834
5.	Zhang Y, Zhou X, Krepinsky JC, Wang C, Segbo J, Zheng F. Association study between fibronectin and coronary heart disease. Clin Chem Lab Med. 2006;44(1):37-42.
6.	Zhang Y, Zheng F, Du H, Krepinsky JC, Segbo JA, Zhou X. Detecting the polymorphisms of paraoxonase (PON) cluster in Chinese Han population based on a rapid method.Clin Chim Acta. 2006 Mar;365(1-2):98-103

Selected Projects:
1.	The distribution of SNPs of FN in atherosclerosis and its effect on EDA domain alternative splicing . Natural Science Foundation of Hubei Province, 2014-2015
2.	The effect of EDA+FN induced ER stress on formation of foam cells in atherosclerosis, Natural Science Foundation of China, 2008-2010
3.	The study of the STAT6 signal conduction involved in regulating colorectal cancer invasion and metastasis,  Natural Science Foundation of China (involved), 2009-2011 Natural Science Foundation of China, 2008-2010 Natural Science Foundation of China, 2008-2010

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Ying ZHANG

Personal Information

Biography

Education

Boards, Advisory Committees, Professional Organizations

Publications

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