Xia ZHAO

Personal Information

Title: Associate Professor

Department: Department of Pathology

Email: yespeony@hust.edu.cn

Clinical Focus: Tumor Pathology

Research Focus/Interests: Cardiovascular Pathology and Molecular Pathology

Biography

Dr. Zhao is an associate professor of Pathology at Tongji Medical College, Huazhong University of Science and Technology. Dr. Zhao studied at Kanazawa Medical University of Japan as a visiting scholar from 2006 to 2007. Her research area focuses on cardiovascular pathology and molecular pathology.

Education

2004-2008   Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, PhD in Pathology
2001-2004   Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, MS in Pathology
1990-1995   Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, BS in Clinical Medicine

Boards, Advisory Committees, Professional Organizations

Member, Committee of Breast Cancer Society, Hubei Anti-cancer Association

Publications

1.	Xiao J, Wang F, Lu H, Xu S, Zou L, Tian Q, Fu Y, Lin X, Liu L, Yuan P, Ni X, Ma T, Zeng F, Xue P, Xiu R, Zhang J, Ji X, Hu H, Lu S, Dai H, Li Y, Chu Q*, Zhao X*, Duan Q*, Zhu F*. Targeting the COX2/MET/TOPK signaling axis induces apoptosis in gefitinib-resistant NSCLC cells. Cell Death Dis. 2019;10(10):777. 
2.	Chen D, Xia Y, Zuo K, Wang Y, Zhang S, Kuang D, Duan Y, Zhao X*, Wang G*. Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration. Sci Rep. 2015; 5: 16813-16821.
3.	Zhao X, Kuang D, Duan Y, Xiao G, Ni J, Duan Y, Wang G. Hyperhomocysteinemia regulated SCF expression in cultured cardiomyocytes via modulation of NF-κB activities. Mol Cell Biochem. 2015; 405(1-2):197-203. 
4.	Zhao X, Nogawa A, Matsunaga T, Takegami T, Nakagawa H, Ishigaki Y*. Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells. Int J Oncol. 2014; 44(1): 222-228.
5.	She T, Wang X, Kuang D, Yue J, Ni J, Chen D, Duan Y, Zhao X*, Wang G*. Hyperglycemia inhibited stem cell factor-induced cardiac stem cell homing to peri-infarcted myocardium via regulating ERK1/2 and p38 MAPK activities. Int J Mol Med. 2012; 30(6): 1313-1320.
6.	Chen Z, Wang J, Zhang H, Liu D, Li Y, Xu Y, Tan D, Chen D, Zhao X*, Wang G*. Topo IIα gene alterations correlated with survival in patients with diffuse large B-cell lymphoma. Eur J Clin Invest. 2012; 42(3): 310-320.
7.	Xia QS, Ishigaki Y, Zhao X, Shimasaki T, Nakajima H, Nakagawa H, Takegami T, Chen ZH, Motoo Y*. Human SMG-1 is involved in gemcitabine-induced primary microRNA-155/BIC up-regulation in human pancreatic cancer PANC-1 cells. Pancreas. 2011; 40(1): 55-60.
8.	Jie W, Guo J, Zhu P,Huang L, Kuang D, Wang X, Li M, Zhao X, Duan Y, Wang G*, Ao Q*. Contribution of CXCR4+/PDGFRβ+ progenitor cells in hypoxic alveolar arterioles muscularization: role of myocardin. Cardiovasc Res. 2010; 87(4): 740-750. 
9.	Kuang D, Zhao X, Xiao G, Ni J, Chen D, Ao Q, Wang G*. Stem cell factor/c-kit signaling mediated cardiac stem cell migration via activation of P38 MARK. Basic Res Cardiol. 2008; 103(3): 265-273.
10.	Nagao A, Zhao X, Takegami T, Nakagawa H, Matsui S, Matsunaga T, Ishigaki Y*. Multiple shRNA expressions in a single plasmid vector improve RNAi against the XPA gene. Biochem Biophys Res Commun. 2008; 370(2):301-305.

Projects:
2012-2015, a novel cardiac kinase TNNI3K may mediate the migration of cardiac stem cells after myocardial infarction, National Natural Science Foundation of China

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Xia ZHAO

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