Xingjiang YU

Personal Information

Title: Professor

Department: Department of Histology and Embryology

Email: yuxingjiang@yahoo.com/yuxingjiang@hust.edu.cn

Clinical Focus:

Research Focus/Interests: Research field: pathogenesis and clinical transformation of cancer stem cells Research direction: 1. the effect of hypoxia microenvironment on the maintenance of cancer stem cells, 2. Cancer stem cell migration and invasion, 3. Cancer stem cell metabolism and angiogenesis. 4. Cancer stem cell and Immunity

Biography

Education

2009-2014    Ph.D.   Institute of Zoology, Chinese Academy of Sciences(CAS), Beijing, China
Professional: Development Biology
Research contents: Molecular mechanism of maternal regulation of early embryo development
Supervisor: Lei Li, Ph.D.

2005-2008   Master    Northeast Agriculture University, Harbin, China
Professional: Development Biology
Research contents: The molecular mechanism of embryo implantation
Supervisor: Hua Ni, Ph.D.

2000-2004   Bachelor    Heilongjiang University, Harbin, China
Professional: Biotechnology

Boards, Advisory Committees, Professional Organizations

Member, Hubei Anatomical Society
Member, Cinese Anatomical Society
Member, Medical Society Of Western Returned Scholars Association

Publications

1.	Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression. Haidong Huang , Xingjiang Yu , Xiangzi Han , Jing Hao , Jianjun Zhao , Gurkan Bebek , Shideng Bao , Richard A Prayson , Ahmad M Khalil , Eckhard Jankowsky , Jennifer S Yu. Cell Reports. 2021 Jan 5;34(1):108522.
2.	Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma. Weiwei Tao W, Chu C, Zhou W, Huang Z, Zhai K, Fang X,  Huang Q, Zhang A, Wang X, Yu X, Huang H, Wu Q, Sloan A.E, Yu JS, Li X,  Stark G.R, Rich J.N & Bao S. Nature Communications. 2020 Jun 15;11(1):3015.
3.	Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling. Dong M, Xiao Q, Hu J, Cheng F, Zhang P, Zong W, Tang Q, Li X, Mao F, He Y, Yu X, Wan F, Lei T, Guo D, Wang B. Cancer Gene Therapy.2020 Jan 28.
4.	Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells. Man J*, Yu X*, Huang H, Zhou W, Xiang C, Huang H, Miele L, Liu Z, Bebek G, Bao S, Yu JS. Cell Stem Cell. 2017 Nov 23. PII: S1934-5909(17)30422-8.  
5.	The subcortical maternal complex controls symmetric division of mouse zygotes by regulating F-actin dynamics. Yu XJ*, Yi Z, Gao Z, Qin D, Zhai Y, Chen X, Ou-Yang Y, Wang ZB, Zheng P, Zhu MS, Wang H, Sun QY, Dean J, Li L. Nature Communications. 2014.Sep.11;5:4887.  
6.	Zbed3 participates in the subcortical maternal complex and regulates the distribution of organelles. Gao Z, Zhang X, Yu X, Qin D, Xiao Y, Yu Y, Xiang Y, Nie X, Lu X, Liu W, Yi Z, Li L. J Mol Cell Biol. 2017 Aug 23.  
7.	BTG4 is a key regulator for maternal mRNA clearance during mouse early embryogenesis. Liu Y, Lu X, Shi J, Yu X, Zhang X, Zhu K, Yi Z, Duan E, Li L. J Mol Cell Biol. 2016 Aug;8(4):366-8.  
8.	Maternal BCAS2 protects genomic integrity in mouse early embryonic development. Xu Q, Wang F, Xiang Y, Zhang X, Zhao ZA, Gao Z, Liu W, Lu X, Liu Y, Yu XJ, Wang H, Huang J, Yi Z, Gao S, Li L. Development. 2015 Nov 15;142(22):3943-53.  
9.	Progesterone regulation of glutathione S-transferase Mu2 expression in mouse uterine luminal epithelium during preimplantation period. Ni H, Yu XJ, Liu HJ, Lei W, Rengaraj D, LiXJ, Yang ZM. Fertil and Steril. 2009 May;91(5 Suppl):2123-30.  
10.	Radiobiology Self-Assessment Guide, Demos Medical, 2016.  Mohamed E.Abazeed; Alex Almasan; Sudha Amarnath; Marc Apple; Ehsan H. Balagamwala; Salim Balik; Elia Bar; Camille Berriochoa; HyeonJoo Cheon; Taoran Cui; Sharvari Dharmaiah; Frank Dong; Andrew Godley; John F. Greskovich; Haidong Huang; Nikhil Joshi; Aditya Juloori; Jeffrey A.Kittel; Susan Kost; Daesung Lee; C.Marc Leyrer; Bindu V. Manyam; Anthony Mastroianni; Mihir Naik; Steven Oh; Yvonne Pham; Peng Qi; Vinay Rao; Richard Blake Ross; Chirag Shah; Matthew C.Ward; Michael A, Weller; Neil Woody; Kevin Wunderle; Choamei Xiang; Kailin Yang; Brian D.Yard; Jennifer S. Yu; Xingjiang Yu.  (学术专著)

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Xingjiang YU

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Publications

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