Xiansong WANG

Personal Information

Title: Associate Professor

Department: Department of Pathology

Email: xiansongw@hust.edu.cn

Clinical Focus: Ultrastructural pathology

Research Focus/Interests: cancer (DNA) vaccine; stem cell and mast cell differentiation; pharmacology of anti-asthmatic drugs

Biography

Dr. Wang is an associate professor at School of Basic Medicine, Tongji Medical College, Huazhong University of Science. His research work involves the development of cancer vaccines (DNA vaccines), the differentiation of stem cells into mast cells, the pharmacology of anti-asthmatic and anti-inflammatory drugs. His area of clinical expertise is ultrastructural pathology.

Education

2004   Chinese University of Hong Kong, PhD in Pharmacology
1996    Tongji Medical University, MS in Pathology
1990    Hubei Medical College Xianning Branch, BS in Clinical Medicine

Positions:
2007-present  Department of Pathology, Tongji Medical College, Huazhong University of Science and Technology, Associate Professor
2004-2007      Department of Pathology, Tongji Medical College, Huazhong University of Science and Technology, Lecture
1999-2000      Institute of Medical Virology, University of Zurich, Visiting Scholar
1996-1999       Department of Ultrastructural Pathology; Tongji Medical University, Lecture
1990-1993       Department of Pathology, Hubei Medical College at Xian’ning, Assistant

Boards, Advisory Committees, Professional Organizations

Publications

1.	Xie Li, Liu AG, Peng LY, Wang SJ, Zhang YP, Wang XS. Expression of E-prostanoid receptors in nasal polyp tissues of smoking and nonsmoking patients with chronic rhinosinusitis. 2018; 13(7): e0200989.    
2.	Xie L, Liu AG, Cui YH, Zhang YP, Liao B, Li NN, Wang XS. Expression profiles of prostaglandin E2 receptor subtypes in aspirin tolerant adult Chinese with chronic hinosinusitis. Am J Rhinol Allergy,  2015; 29(5): 322-8.  
3.	Wang XS, Wu AY, Leung PS, Lau HY. PGE suppresses excessive anti-IgE induced cysteinyl leucotrienes production in mast cells of patients with aspirin exacerbated respiratory disease. Allergy, 2007; 62: 620-627. 
4.	Wang XS, Lau HY. Histamine release from human buffy coat-derived mast cells. Int Immunopharmacol, 2007; 7: 541-546. 
5.	Wang XS, Lau HY. β-adrenoceptor-mediated inhibition of mediator release from human peripheral blood-derived mast cells. Clin Exp Pharmacol Physiol, 2006; 33: 746-750. 
6.	Wang XS, Sze Wing Sam, Kwok Ho Yip, Lau HY. Functional characterization of human mast cells cultured from adult peripheral blood. Int Immunopharmacol, 2006; 6: 839-847. 
7.	Wang XS, Lau HY. Prostaglandin E potentiates the immunologically stimulated histamine release from human peripheral blood-derived mast cells through EP1/EP3 receptors. Allergy, 2006; 61: 503-506. 
8.	Wang XS, Yip KH, Sam SW, Lau HY. Buffy coat preparation is a convenient source of progenitors for culturing mature human mast cells. J Immunol Methods, 2006; 309: 69-74.
9.	Wang XS, Sheng Z, Ruan YB, Guan Y, Yang ML. CpG oligodeoxynucleotides inhibit tumor growth and reverse the immunosuppression caused by the therapy with 5-fluorouracil in murine hepatoma. World J Gastroenterol，2005; 11: 1220-1224.

Projects:
1. The therapeutic potential of CpG-containing oligodeoxynucleotides in combination of chemotherapeutic drugs in murine hepatoma. Natural Science Foundation of Hubei Province, 2000-2002
2. Expression and function of EP receptors in mast cells cultured from human peripheral blood progenitors under the inflammatory microenvironment, Natural Science Foundation of China (Project No. 3067092)
3. Study of phenotypic differentiation and functional characteristics of mast cells cultured from human peripheral blood under the inflammatory or non-inflammatory conditions in the mimic human airway tissues, Natural Science Foundation of China (Project No. 81270062)

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Xiansong WANG

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