Jing QU

Personal Information

Title: Associate Professor

Department: Department of Pathophysiology

Email: jingqu@hust.edu.cn

Clinical Focus:

Research Focus/Interests: to understand the role of biomechanical signaling in the regulation of tissue injury, repair/remodeling and regeneration, in particular in the disease processes of human idiopathic pulmonary fibrosis

Biography

Education

Ph.D., Wuhan University, Wuhan, China
postdoctoral training, the University of Alabama at Birmingham

Boards, Advisory Committees, Professional Organizations

Member, American Heart Association
Member, American Thoracic Society

Publications

1.	Qu J*（Co-corresponding author）, Yang S, Zhu Y, Thannickal VJ, Zhou Y*. Targeting Mechanosensitive MDM4 Promotes Lung Fibrosis Resolution in Aged Mice. 2021. JEM 10.1084
2.	Qu J, Yang zhenhua. Protocol to produce high-titer retrovirus for transduction of mouse bone marrow cells. 2021. STAR Protoc. 2021 Jun 18; 2(2): 100459.
3.	Zhou Z, Qu J, He L, Zhu Y, Yang S, Zhang F, Guo T, Peng H, Chen P, Zhou Y. Stiff Matrix Instigates Type I Collagen Biogenesis by Mammalian Cleavage Factor I Complex-Mediated Alternative Polyadenylation. JCI insight. January. 2020. 133972
4.	Zhu Y, Qu J*（Corresponding author）, He L, Zhang F, Zhou Z, Yang S, Zhou Y. Calcium Role in Vascular Smooth Muscle Cell Elasticity and Adhesion. Frontiers in physiology. 07 August 2019.
5.	Zhang F, Liu K, Cao M, Qu J, Zhou D, Pan Z, Duan G, Zhou Y. Rosiglitazone treatment prevents postoperative fibrosis in a rabbit model of glaucoma filtration surgery. Invest Ophthalmol Vis Sci. June 2019, Vol.60, 2743-2752. 
6.	Patrick Ernst, Xu N, Qu J, Chen H, Goldberg M, Zhang J, O'Rourke B, Liu X, and Zhou L. Precisely Control Mitochondria with Light to Manipulate Cell Fate Decision. Biophysical Journal. 20 August 2019, 631-645.
7.	Zhu Y, He L, Qu J, Zhou Y. Regulation of Vascular Smooth Muscle Cell Stiffness and Adhesion by [Ca2+]i: An Atomic Force Microscopy-Based Study. Microscopy and Microanalysis. 2018, 708-712. 
8.	Zhou Z, Qu J, He L, Peng H, Chen P, Zhou Y. α6-Integrin alternative splicing: distinct cytoplasmic variants in stem cell fate specification and niche interaction. Stem Cell Research & Therapy. 2018, 9:122.
9.	Qu J, Zhu L, Zhou Z, Liu S, Locy M, Thannickal VJ, Zhou Y.  Reversing Mechanoinductive Desmoplakin (DSP) Expression by CRISPR/dCas9-Mediated Epigenome Editing. Am J Respir Crit Care Med. 20-June-2018 as 10.1164/rccm.
10.	Chen H#, Qu J#（Co-first author）, Huang X, Kurundkar A, Zhu L, Yang N, Venado A, Ding Q, Liu G, Antony VB, Thannickal VJ, Zhou Y.  Mechanosensing by the Alpha6 Integrin Confers an Invasive Fibroblast Phenotype and Mediates Lung Fibrosis. Nat Commun. 2016. Aug 18;7:12564.
11.	Qu J, Chen H, Zhu L, Ambalavanan N, Girkin C, Murphy-Ullrich J, Downs J and Zhou Y. High-Magnitude and/or High-Frequency Mechanical Strain Promotes Peripapillary Scleral Myofibroblast Differentiation. Invest Ophthalmol Vis Sci. 2015 Dec 1;56(13):7821-30. doi: 10.1167/iovs.15-17848.
12.	Goh K, Qu J, Liu T, Dell'Italia L, Wu Y, O'Rourke B, Zhou L. Impaired Mitochondrial Network Excitability in Failing Guinea Pig Cardiomyocytes. Cardiovasc Res. 2015 Oct 3. pii: cvv230.
13.	Liu J, Wang P, Zou L, Qu J, Litovsky S, Umeda P, Zhou L, Chatham J, Marsh SA, Dell'Italia LJ, Lloyd SG. High-fat, low-carbohydrate diet promotes arrhythmic death and increases myocardial ischemia-reperfusion injury in rats. Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H598-608.
14.	Collins HE1, He L, Zou L, Qu J, Zhou L, Litovsky SH, Yang Q, Young ME, Marchase RB, Chatham JC. Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function. Am J Physiol Heart Circ Physiol. 2014 Apr 15;306(8):H1231-9.
15.	Li Y, Zhang Q, Liu Y, Luo Z, Kang L, Qu J, Liu W, Xia X, Liu Y, Wu K, Wu J. Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways. J. Virol. 2012, 86(23):12531.
16.	Zhang Q, Gong R, Qu J, Zhou Y, Liu W, Chen M, Liu Y, Zhu Y, Wu J. Activation of the Ras/Raf/MEK pathway facilitates HCV replication via attenuation of the INF-JAK-STAT pathway. J. Virol. 2012, 86(3):1544.
17.	Qu J, Zhang Q, Li Y, Liu W, Chen L, Zhu Y, Wu J. Human immunodeficiency virus-1 transactivator of transcription enhances hepatitis C virus replication in an interferon gamma-inducible protein 10-dependent manner. BMC Immunology 2012, 13:15.
18.	Qu J, Yang Z, Zhang Q, Liu W, Li Y, Ding Q, Liu F, Liu Y, Pan Z, He B, Zhu Y, Wu J. Human immunodeficiency virus-1 Rev protein activates hepatitis C virus gene expression by directly targeting the HCV 5’-untranslated region. FEBS Letters. 585, 2011, 4002–4009.

Navigate on the page

Personal Information
Biography
Education
Boards, Advisory Committees, Professional Organizations
Publications

Jing QU

Personal Information

Biography

Education

Boards, Advisory Committees, Professional Organizations

Publications

Navigate on the page

About BMS

Faculty

Research

Education & Admissions

News & Events