Ping LEI

Personal Information

Title: Professor

Department: Department of Immunology

Email: adaleip@hust.edu.cn

Clinical Focus:

Research Focus/Interests: Prof. Lei’s research fields are about manipulating the tumor microenvironment and antibody engineering. She has presided various projects supported by NSFC, Chinesisch-Deutsche Zentrum für Wissenschaftsförderung, National High-tech R&D Program of China, the Doctoral Program of Higher Education of China, and several projects by the Fundamental Research Funds for the Central Universities.

Biography

07/2005 – present   Lecturer, Associate Professor, Professor, Tongji Medical College, HUST
07/1997-08/2000   Teaching Assistant, Medical Experimental Center, Tongji Medical University

Education

09/2000 – 06/2005   Ph.D, Tongji Medical College, HUST
09/1992 – 07/1997   B.S in Clinical Medicine, Tongji Medical University

Boards, Advisory Committees, Professional Organizations

Committee Member, Cell Research and Therapy of Chinese Research Hospital Association
Committee Member, Hubei Society of Immunology
Committee Member, Wuhan Society of Immunology
Vice president, Medical Education of Hubei Society of Medical Bio-Immunology

Publications

1.	Jiaxu Zhu#, Yaqun Jiang#, Xin Pan, Kui Xu, Wenhao Niu, Yibing Lv, Chongjiao Li, Yichun Wang, Zejian Xue, Ping Lei*, and Yong He*. In Vivo Evaluation of a Gallium-68-Labeled Tumor-Tracking Cyanine Dye for Positron Emission Tomography/Near-Infrared Fluorescence Carcinoma Imaging, Image-Guided Surgery, and Photothermal Therapy. ACS Omega. 2023 Feb 3;8(6):6067-6077. 
2.	Zhao L#, Lv Y#, Zhou X, Guo Z, Li H, Guo Y, Liu T, Tu L, Zhu L, Tao J, Shen G, He Y* and Lei P* (2023). Secreted glucose regulated protein78 ameliorates DSS-induced mouse colitis. Front Immunol. 14:986175.    
3.	Zhou X#, Ye G#, Lv Y, Guo Y, Pan X, Li Y, Shen G, He Y*, Lei P*. IL-6 drives T cell death to participate in lymphopenia in COVID-19. Int Immunopharmacol. 2022 Oct; 111:109132. 
4.	Wu Z#, Xu Z#, Zhou X, Li H, Zhao L, Lv Y, Guo Y, Shen G, He Y*, Lei P*. sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death. Cell Death Dis. 2022 Jul 7;13(7):587.  
5.	Wu Z#, Zhou J#, Xiao Y#, Ming J, Zhou J, Dong F, Zhou X, Xu Z, Zhao X*, Lei P*, Huang T*. CD20+CD22+ADAM28+ B Cells in Tertiary Lymphoid Structures Promote Immunotherapy Response. Front Immunol. 2022 Mar 11; 13:865596.    
6.	Huiming Peng#, Jian Shen#, Xin Long, Xiaoqi Zhou, Jiaqi Zhang, Xina Xu, Teng Huang, Hui Xu, Shuguo Sun, Chun Li, Ping Lei*, Heshui Wu*, Jun Zhao*. Local Release of TGF-β Inhibitor Modulates Tumor-Associated Neutrophils and Enhances Pancreatic Cancer Response to Combined Irreversible Electroporation and Immunotherapy. Adv Sci (Weinh). 2022 Apr;9(10):e2105240.  
7.	Zhou X, Yang M, Lv Y, Li H, Wu S, Min J, Shen G, He Y*, Lei P*. Adoptive transfer of GRP78-treated dendritic cells alleviates insulitis in NOD mice. J Leukoc Biol. 2021 Dec; 110(6): 1023-1031.     
8.	Guo Z#, Zhang Y#, Fu M, Zhao L, Wang Z, Xu Z, Zhu H, Lan X, Shen G, He Y*, Lei P*. The Transferrin Receptor-Directed CAR for the Therapy of Hematologic Malignancies. Front Immunol. 2021 Mar 29; 12:652924.  
9.	Zhang J, Wang Z, Wang X, Hu Z, Yang C*, Lei P*. Risk Factors for Mortality of COVID-19 Patient Based on Clinical Course: A Single Center Retrospective Case-Control Study. Front Immunol. 2021 Feb 16; 12:581469.  
10.	Chen L, Zheng H, Yu X, Liu L,Li H, Zhu H, Zhang Z, Lei P*, Shen G. Tumor-Secreted GRP78 Promotes the Establishment of a Pre-metastatic Niche in the Liver Microenvironment. Front Immunol. 2020 Sep 29; 11:584458. 
11.	Wu Z#, Zhang Z#, Lei Z, Lei P*. CD14: Biology and Role in the pathogenesis of disease. Cytokine Growth Factor Rev. 2019 Aug; 48:24-31. 
12.	Fu M#, He Q#, Guo Z, Zhou X, Li H, Zhao L, Tang H, Zhou X, Zhu H, Shen G, He Y*, Lei P*. Therapeutic Bispecific T-Cell Engager Antibody Targeting the Transferrin Receptor. Front Immunol. 2019 Jun 21; 10:1396.

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Ping LEI

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