Yanhong LIAO

Personal Information

Title: Professor

Department: Department of Anatomy

Email: yhliao1@hust.edu.cn

Clinical Focus:

Research Focus/Interests:

Biography

07/1990-10/1995: Teaching assistant & Lecturer at Department of Microbiology, Tongji Medical University
10/1995-10/1996: Visiting fellow in Hygiene Institute, Karl-Franzens University Graz (Graz, Austria).
10/1996-03/1997: Pre-doctoral trainee at Department of Physiology, School of Medicine, Kobe University (Kobe, Japan).
08/2001-04/2002: Postdoc at Department of Anesthesiology, School of Medicine, UCLA (LA, USA).
04/2002-12/2008: Research fellow in Branch of Signal Transduction, National Institute of Environmental Health and Sciences (NIEHS, RTP, NC).
01/2009-present: Professor at Department of Anatomy, Tongji Medical College Huazhong University of Science and Technology.

Education

09/1982-07/1987   Bachelor, School of Public Health, Tongji Medical University
09/1987-07/1990   Msc in Microbiology, Tongji Medical University
04/1997-04/2001   PhD in Physiology, School of Medicine, Kobe University, Japan

Boards, Advisory Committees, Professional Organizations

Publications

1.	Zhang YH, Yin NN, Sun AB, Wu QF, Hu WZ, Hou X, Zeng XX, Zhu M, and Liao Y. Transient Receptor Potential Channel 6 Knockout Ameliorates Kidney Fibrosis by Inhibition of Epithelial-Mesenchymal Transition. Front Cell Dev Biol. 2021 Jan 15;8: 602703. doi: 10.3389/fcell.2020.602703. eCollection 2020.
2.	Hou X, Xiao HT, Zhang YH, Zeng XX, Huang MJ, Chen XY, Birnbaumer L, Liao Y. Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation. Cell Death Dis. 2018 Oct 2018 Oct 3; 9 (10):1015. doi: 10.1038/s41419-018-1052-5.
3.	He X, Li S, Liu B, Susperreguy S, Formoso K, Yao J, Kang J, Shi A, Birnbaumer L, Liao Y. Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries. PNAS 2017 Jun 6; 114 (23):E4582-E4591.
4.	Chen X, Lu M, He X, Ma L, Birnbaumer L, Liao Y.  TRPC3/6/7 Knockdown Protects the Brain from Cerebral Ischemia Injury via Astrocyte Apoptosis Inhibition and Effects on NF-кB Translocation. Mol Neurobiol. 2016 Nov 8. [Epub ahead of print]
5.	Liao Y, Plummer NW, George MD, Abramowitz J, Zhu MX, Birnbaumer L. PNAS. 2009 Mar 3;106(9):3202-6. doi: 10.1073/pnas.0813346106. Epub 2009 Feb 12
6.	Liao Y, Erxleben C, Abramowitz J, Flockerzi V, Zhu MX, Armstrong D, and Birnbaumer L. Functional interactions among Orai1, TRPCs and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels.  PNAS 2008，105 （8）2895-900
7.	Liao Y, Erxleben C, Yildirim E, Abramowitz J, Armstrong DL, and Birnbaumer L. Orai proteins interact with TRPC channels and confer responsiveness to store depletion. PNAS 2007 Mar 13; 104 (11):  4682-87
8.	Liao Y, Satoh T, Gao X, Jin TG, Hu CD, Kataoka T. RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1-GTP and enhances Rap1-dependent B-Raf activation. J Biol Chem 2001 Jul 27; 276(30):28478-83
9.	Liao Y, Kariya K, Hu CD, Shibatohge M, Goshima M, Okada T, Watari Y, Gao X, Jin TG, Yamawaki-Kataoka Y, Kataoka T.RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans. J Biol Chem 1999 Dec 31; 274(53):37815-20

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Yanhong LIAO

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