On the morning of November 25, Prof. Bin Zhang, director of Mount Sinai Center for Transformative Disease Modeling, gave a report entitled "Identification and Characterization of Molecular Subtypes of Alzheimer's Disease" under the invitation of Prof. Xiaochuan Wang and Prof. Rong Liu at the Department of Pathophysiology, School of Basic Medicine.
Prof. Xiaochuan Wang first gave a brief introduction to the speaker Prof. Bin Zhang who is an internationally renowned expert in genetics & genomic sciences and molecular bioinformatics. Prof. Zhang focuses on the research of neurological disease systems biology. In the past 5 years, he has hosted nearly ten NIH projects and participated in more than ten with a total funding of 35 million dollars. He has published highly-cited papers in top journals including Nature, Science, Cell, Nature Genetic, PNAS, Neuron, Science Advances, and Molecular Psychiatry.
In his report, Prof. Zhang introduced the latest research findings of his team. Their study has revealed key molecular changes in Alzheimer’s Disease, systematically established a multi-level gene regulatory network model, discovered new molecular mechanisms and potential new directions for drug development, thus laying a new foundation for a comprehensive exploration of the pathogenesis of Alzheimer's Disease and the development of effective targeted drugs.
This online academic report is supported by joint research platform incubation program of Huazhong University of Science and Technology. It builds a platform for international communication, broadens students' horizon, and lays a solid foundation for scholars from both sides to continue their close cooperation in the future.